Human Dermis Harbors Distinct Mesenchymal Stromal Cell Subsets
نویسندگان
چکیده
منابع مشابه
Human Dermis Harbors Distinct Mesenchymal Stromal Cell Subsets
Multipotent mesenchymal stromal cells (MSCs) are found in a variety of adult tissues including human dermis. These MSCs are morphologically similar to bone marrow-derived MSCs, but are of unclear phenotype. To shed light on the characteristics of human dermal MSCs, this study was designed to identify and isolate dermal MSCs by a specific marker expression profile, and subsequently rate their me...
متن کاملDistinct mesenchymal progenitor cell subsets in the adult human synovium.
OBJECTIVE To analyse the heterogeneity at the single-cell level of human mesenchymal progenitor cells from SM. METHODS Cell populations were enzymatically released from the knee joint synovium of adult human individuals. Single cell-derived clonal populations were obtained by limiting dilution and serially passaged to determine growth rates. Phenotypic analysis was carried out by flow cytomet...
متن کاملResponse of human chondrocytes and mesenchymal stromal cells to a decellularized human dermis
BACKGROUND Although progress has been made in the treatment of articular cartilage lesions, they are still a major challenge because current techniques do not provide satisfactory long-term outcomes. Tissue engineering and the use of functional biomaterials might be an alternative regenerative strategy and fulfill clinical needs. Decellularized extracellular matrices have generated interest as ...
متن کاملP-58: Mesenchymal Stromal Cell Cultures from Human Testis Tissue Cryopreservation and Their Potential for The Future Cell Therapy Applications
N;
متن کاملThe human kidney capsule contains a functionally distinct mesenchymal stromal cell population
We recently demonstrated that the adult human kidney cortex contains a perivascular stromal cell (kPSC) that shows organotypic properties and is important for repair and stabilisation of kidney function. Not only the kidney cortex but also the kidney capsule contains stromal cells that are important for the three dimensional organisation of the kidney during nephrogenesis. They provide the barr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2012
ISSN: 0022-202X
DOI: 10.1038/jid.2011.355